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Genotype-dependent associations between serotonin transporter gene (SLC6A4) DNA methylation and late-life depression

BACKGROUND: Disrupted serotonergic signaling is often a feature of depression and the role of the serotonin transporter gene (SLC6A4), responsible for serotonin re-uptake, has received much attention in this regard. Most studies have focused on the polymorphic 5-HTTLPR upstream repeat, or DNA methyl...

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Detalles Bibliográficos
Autores principales:	Lam, Dilys, Ancelin, Marie-Laure, Ritchie, Karen, Freak-Poli, Rosanne, Saffery, Richard, Ryan, Joanne
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6122720/ https://www.ncbi.nlm.nih.gov/pubmed/30180828 http://dx.doi.org/10.1186/s12888-018-1850-4

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