The human lymph node microenvironment unilaterally regulates T-cell activation and differentiation

The microenvironment of lymphoid organs can aid healthy immune function through provision of both structural and molecular support. In mice, fibroblastic reticular cells (FRCs) create an essential T-cell support structure within lymph nodes, while human FRCs are largely unstudied. Here, we show that...

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Detalles Bibliográficos
Autores principales: Knoblich, Konstantin, Cruz Migoni, Sara, Siew, Susan M., Jinks, Elizabeth, Kaul, Baksho, Jeffery, Hannah C., Baker, Alfie T., Suliman, Muath, Vrzalikova, Katerina, Mehenna, Hisham, Murray, Paul G., Barone, Francesca, Oo, Ye H., Newsome, Philip N., Hirschfield, Gideon, Kelly, Deirdre, Lee, Steven P., Parekkadan, Biju, Turley, Shannon J., Fletcher, Anne L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Short Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6122729/
https://www.ncbi.nlm.nih.gov/pubmed/30180168
http://dx.doi.org/10.1371/journal.pbio.2005046

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