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Nrf2 activation drive macrophages polarization and cancer cell epithelial-mesenchymal transition during interaction

BACKGROUND: The M2 phenotype of tumor-associated macrophages (TAM) inhibits the anti-tumor inflammation, increases angiogenesis and promotes tumor progression. The transcription factor Nuclear Factor (erythroid-derived 2)-Like 2 (Nrf2) not only modulates the angiogenesis but also plays the anti-infl...

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Detalles Bibliográficos
Autores principales:	Feng, Rui, Morine, Yuji, Ikemoto, Tetsuya, Imura, Satoru, Iwahashi, Shuichi, Saito, Yu, Shimada, Mitsuo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6122794/ https://www.ncbi.nlm.nih.gov/pubmed/30180849 http://dx.doi.org/10.1186/s12964-018-0262-x

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