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Anticancer activity of paclitaxel-loaded keratin nanoparticles in two-dimensional and perfused three-dimensional breast cancer models
PURPOSE: Taxanes are highly effective cytotoxic drugs for progressing breast cancer treatment. However, their poor solubility and high toxicity urge the development of innovative formulations of potential clinical relevance. MATERIALS AND METHODS: By using a simple and straightforward aggregation me...
Autores principales: | Foglietta, Federica, Spagnoli, Giulio C, Muraro, Manuele Giuseppe, Ballestri, Marco, Guerrini, Andrea, Ferroni, Claudia, Aluigi, Annalisa, Sotgiu, Giovanna, Varchi, Greta |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6122896/ https://www.ncbi.nlm.nih.gov/pubmed/30214193 http://dx.doi.org/10.2147/IJN.S159942 |
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