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Pioglitazone Induces Cardiomyocyte Apoptosis and Inhibits Cardiomyocyte Hypertrophy Via VEGFR-2 Signaling Pathway

BACKGROUND: Pioglitazone has been widely used as an insulin-sensitizing agent for improving glycemic control in patients with type 2 diabetes mellitus. However, cardiovascular risk and protective effects of pioglitazone remain controversial. OBJECTIVES: In this study, we investigated whether pioglit...

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Detalles Bibliográficos
Autores principales: Zhong, Wenliang, Jin, Wen, Xu, Shanghua, Wu, Yanqing, Luo, Shunxiang, Liang, Minlie, Chen, Lianglong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Cardiologia - SBC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6122905/
https://www.ncbi.nlm.nih.gov/pubmed/29972411
http://dx.doi.org/10.5935/abc.20180108

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