Infrapatellar Fat Pad-Derived Stem Cell-Based Regenerative Strategies in Orthopedic Surgery

Infrapatellar fat pad is a densely vascularized and innervated extrasynovial tissue that fills the anterior knee compartment. It plays a role in knee biomechanics as well as constitutes a source of stem cells for regeneration after knee injury. Infrapatellar fat pad-derived stem cells (IPFP-ASCs) po...

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Detalles Bibliográficos
Autores principales: Huri, Pinar Yilgor, Hamsici, Seren, Ergene, Emre, Huri, Gazi, Doral, Mahmut Nedim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Knee Society 2018
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6122943/
https://www.ncbi.nlm.nih.gov/pubmed/29554720
http://dx.doi.org/10.5792/ksrr.17.061
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author Huri, Pinar Yilgor
Hamsici, Seren
Ergene, Emre
Huri, Gazi
Doral, Mahmut Nedim
author_facet Huri, Pinar Yilgor
Hamsici, Seren
Ergene, Emre
Huri, Gazi
Doral, Mahmut Nedim
author_sort Huri, Pinar Yilgor
collection PubMed
description Infrapatellar fat pad is a densely vascularized and innervated extrasynovial tissue that fills the anterior knee compartment. It plays a role in knee biomechanics as well as constitutes a source of stem cells for regeneration after knee injury. Infrapatellar fat pad-derived stem cells (IPFP-ASCs) possess enhanced and age-independent differentiation capacity as compared to other stem cells, which makes them a very promising candidate in stem cell-based regenerative therapy. The aims of this review are to outline the latest advances and potential trends in using IPFP-ASCs and to emphasize the advantages over other sources of stem cells for applications in orthopedic surgery.
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spelling pubmed-61229432018-09-12 Infrapatellar Fat Pad-Derived Stem Cell-Based Regenerative Strategies in Orthopedic Surgery Huri, Pinar Yilgor Hamsici, Seren Ergene, Emre Huri, Gazi Doral, Mahmut Nedim Knee Surg Relat Res Review Article Infrapatellar fat pad is a densely vascularized and innervated extrasynovial tissue that fills the anterior knee compartment. It plays a role in knee biomechanics as well as constitutes a source of stem cells for regeneration after knee injury. Infrapatellar fat pad-derived stem cells (IPFP-ASCs) possess enhanced and age-independent differentiation capacity as compared to other stem cells, which makes them a very promising candidate in stem cell-based regenerative therapy. The aims of this review are to outline the latest advances and potential trends in using IPFP-ASCs and to emphasize the advantages over other sources of stem cells for applications in orthopedic surgery. Korean Knee Society 2018-09 2018-09-01 /pmc/articles/PMC6122943/ /pubmed/29554720 http://dx.doi.org/10.5792/ksrr.17.061 Text en Copyright © 2018 Korean Knee Society This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Huri, Pinar Yilgor
Hamsici, Seren
Ergene, Emre
Huri, Gazi
Doral, Mahmut Nedim
Infrapatellar Fat Pad-Derived Stem Cell-Based Regenerative Strategies in Orthopedic Surgery
title Infrapatellar Fat Pad-Derived Stem Cell-Based Regenerative Strategies in Orthopedic Surgery
title_full Infrapatellar Fat Pad-Derived Stem Cell-Based Regenerative Strategies in Orthopedic Surgery
title_fullStr Infrapatellar Fat Pad-Derived Stem Cell-Based Regenerative Strategies in Orthopedic Surgery
title_full_unstemmed Infrapatellar Fat Pad-Derived Stem Cell-Based Regenerative Strategies in Orthopedic Surgery
title_short Infrapatellar Fat Pad-Derived Stem Cell-Based Regenerative Strategies in Orthopedic Surgery
title_sort infrapatellar fat pad-derived stem cell-based regenerative strategies in orthopedic surgery
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6122943/
https://www.ncbi.nlm.nih.gov/pubmed/29554720
http://dx.doi.org/10.5792/ksrr.17.061
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