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LPS inactivation by a host lipase allows lung epithelial cell sensitization for allergic asthma

Allergic asthma is a chronic inflammatory disease primarily mediated by Th2 immune mechanisms. Numerous studies have suggested that early life exposure to lipopolysaccharide (LPS) is negatively associated with allergic asthma. One proposed mechanism invokes desensitization of lung epithelial cells b...

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Detalles Bibliográficos
Autores principales: Qian, Guojun, Jiang, Wei, Zou, Benkun, Feng, Jintao, Cheng, Xiaofang, Gu, Jie, Chu, Tianqing, Niu, Chen, He, Rui, Chu, Yiwei, Lu, Mingfang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6122967/
https://www.ncbi.nlm.nih.gov/pubmed/30021797
http://dx.doi.org/10.1084/jem.20172225