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Transcription factor Etv6 regulates functional differentiation of cross-presenting classical dendritic cells

An IRF8-dependent subset of conventional dendritic cells (cDCs), termed cDC1, effectively cross-primes CD8(+) T cells and facilitates tumor-specific T cell responses. Etv6 is an ETS family transcription factor that controls hematopoietic stem and progenitor cell (HSPC) function and thrombopoiesis. W...

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Detalles Bibliográficos
Autores principales:	Lau, Colleen M., Tiniakou, Ioanna, Perez, Oriana A., Kirkling, Margaret E., Yap, George S., Hock, Hanno, Reizis, Boris
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Rockefeller University Press 2018
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6122974/ https://www.ncbi.nlm.nih.gov/pubmed/30087163 http://dx.doi.org/10.1084/jem.20172323

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