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BCAP links IL-1R to the PI3K–mTOR pathway and regulates pathogenic Th17 cell differentiation
The toll-like receptor (TLR) and interleukin (IL)–1 family of receptors share several signaling components, including the most upstream adapter, MyD88. We previously reported the discovery of B cell adapter for phosphoinositide 3-kinase (BCAP) as a novel toll–IL-1 receptor homology domain–containing...
Autores principales: | Deason, Krystin, Troutman, Ty Dale, Jain, Aakanksha, Challa, Dilip K., Mandraju, Rajakumar, Brewer, Travis, Ward, E. Sally, Pasare, Chandrashekhar |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6122979/ https://www.ncbi.nlm.nih.gov/pubmed/30093533 http://dx.doi.org/10.1084/jem.20171810 |
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