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Cystamine and cysteamine as inhibitors of transglutaminase activity in vivo

Cystamine is commonly used as a transglutaminase inhibitor. This disulphide undergoes reduction in vivo to the aminothiol compound, cysteamine. Thus, the mechanism by which cystamine inhibits transglutaminase activity in vivo could be due to either cystamine or cysteamine, which depends on the local...

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Detalles Bibliográficos
Autores principales: Jeitner, Thomas M., Pinto, John T., Cooper, Arthur J.L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6123069/
https://www.ncbi.nlm.nih.gov/pubmed/30054429
http://dx.doi.org/10.1042/BSR20180691

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