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Improving accuracy for stereotactic body radiotherapy treatments of spinal metastases

PURPOSE: Use of SBRT techniques is now a relatively common recourse for spinal metastases due to good local control rates and durable pain control. However, the technique has not yet reached maturity for gantry‐based systems, so work is still required in finding planning approaches that produce opti...

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Autores principales: Rijken, James, Jordan, Barry, Crowe, Scott, Kairn, Tanya, Trapp, Jamie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6123175/
https://www.ncbi.nlm.nih.gov/pubmed/29943895
http://dx.doi.org/10.1002/acm2.12395
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author Rijken, James
Jordan, Barry
Crowe, Scott
Kairn, Tanya
Trapp, Jamie
author_facet Rijken, James
Jordan, Barry
Crowe, Scott
Kairn, Tanya
Trapp, Jamie
author_sort Rijken, James
collection PubMed
description PURPOSE: Use of SBRT techniques is now a relatively common recourse for spinal metastases due to good local control rates and durable pain control. However, the technique has not yet reached maturity for gantry‐based systems, so work is still required in finding planning approaches that produce optimum conformity as well as delivery for the slew of treatment planning systems and treatment machines. METHODS: A set of 32 SBRT spine treatment plans based on four vertebral sites, varying in modality and number of control points, were created in Pinnacle. These plans were assessed according to complexity metrics and planning objectives as well as undergoing treatment delivery QA on an Elekta VersaHD through ion chamber measurement, ArcCheck, film‐dose map comparison and MLC log‐file reconstruction via PerFraction. RESULTS: All methods of QA demonstrated statistically significant agreement with each other (r = 0.63, P < 0.001). Plan complexity and delivery accuracy were found to be independent of MUs (r = 0.22, P > 0.05) but improved with the number of control points (r = 0.46, P < 0.03); with use of 90 control points producing the most complex and least accurate plans. The fraction of small apertures used in treatment had no impact on plan quality or accuracy (r = 0.29, P > 0.05) but rather more complexly modulated plans showed poorer results due to MLC leaf position inaccuracies. Plans utilizing 180 and 240 control points produced optimal plan coverage with similar complexity metrics to each other. However, plans with 240 control points demonstrated slightly better delivery accuracy, with fewer MLC leaf position discrepancies. CONCLUSION: In contrast to other studies, MU had no effect on delivery accuracy, with the most impactful parameter at the disposal of the planner being the number of control points utilized.
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spelling pubmed-61231752018-09-10 Improving accuracy for stereotactic body radiotherapy treatments of spinal metastases Rijken, James Jordan, Barry Crowe, Scott Kairn, Tanya Trapp, Jamie J Appl Clin Med Phys Radiation Oncology Physics PURPOSE: Use of SBRT techniques is now a relatively common recourse for spinal metastases due to good local control rates and durable pain control. However, the technique has not yet reached maturity for gantry‐based systems, so work is still required in finding planning approaches that produce optimum conformity as well as delivery for the slew of treatment planning systems and treatment machines. METHODS: A set of 32 SBRT spine treatment plans based on four vertebral sites, varying in modality and number of control points, were created in Pinnacle. These plans were assessed according to complexity metrics and planning objectives as well as undergoing treatment delivery QA on an Elekta VersaHD through ion chamber measurement, ArcCheck, film‐dose map comparison and MLC log‐file reconstruction via PerFraction. RESULTS: All methods of QA demonstrated statistically significant agreement with each other (r = 0.63, P < 0.001). Plan complexity and delivery accuracy were found to be independent of MUs (r = 0.22, P > 0.05) but improved with the number of control points (r = 0.46, P < 0.03); with use of 90 control points producing the most complex and least accurate plans. The fraction of small apertures used in treatment had no impact on plan quality or accuracy (r = 0.29, P > 0.05) but rather more complexly modulated plans showed poorer results due to MLC leaf position inaccuracies. Plans utilizing 180 and 240 control points produced optimal plan coverage with similar complexity metrics to each other. However, plans with 240 control points demonstrated slightly better delivery accuracy, with fewer MLC leaf position discrepancies. CONCLUSION: In contrast to other studies, MU had no effect on delivery accuracy, with the most impactful parameter at the disposal of the planner being the number of control points utilized. John Wiley and Sons Inc. 2018-06-26 /pmc/articles/PMC6123175/ /pubmed/29943895 http://dx.doi.org/10.1002/acm2.12395 Text en © 2018 Genesis Care. Journal of Applied Clinical Medical Physics published by Wiley Periodicals, Inc. on behalf of American Association of Physicists in Medicine. This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Radiation Oncology Physics
Rijken, James
Jordan, Barry
Crowe, Scott
Kairn, Tanya
Trapp, Jamie
Improving accuracy for stereotactic body radiotherapy treatments of spinal metastases
title Improving accuracy for stereotactic body radiotherapy treatments of spinal metastases
title_full Improving accuracy for stereotactic body radiotherapy treatments of spinal metastases
title_fullStr Improving accuracy for stereotactic body radiotherapy treatments of spinal metastases
title_full_unstemmed Improving accuracy for stereotactic body radiotherapy treatments of spinal metastases
title_short Improving accuracy for stereotactic body radiotherapy treatments of spinal metastases
title_sort improving accuracy for stereotactic body radiotherapy treatments of spinal metastases
topic Radiation Oncology Physics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6123175/
https://www.ncbi.nlm.nih.gov/pubmed/29943895
http://dx.doi.org/10.1002/acm2.12395
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