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A novel glycosylated anti-CD20 monoclonal antibody from transgenic cattle
The monoclonal antibody (mAb) against CD20 known as Rituxan is widely used to treat autoimmune diseases and lymphomas. However, further application of Rituxan faces challenges of high production cost, which limits its availability in developing countries. Here, we report a new approach for large pro...
Autores principales: | Zhang, Ran, Tang, Chenjun, Guo, Huaizu, Tang, Bo, Hou, Sheng, Zhao, Lei, Wang, Jianwu, Ding, Fangrong, Zhao, Jianmin, Wang, Haiping, Chen, Zhongzhou, Dai, Yunping, Li, Ning |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6123398/ https://www.ncbi.nlm.nih.gov/pubmed/30181542 http://dx.doi.org/10.1038/s41598-018-31417-2 |
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