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Cochaperones enable Hsp70 to use ATP energy to stabilize native proteins out of the folding equilibrium
The heat shock protein 70 (Hsp70) chaperones, vital to the proper folding of proteins inside cells, consume ATP and require cochaperones in assisting protein folding. It is unclear whether Hsp70 can utilize the free energy from ATP hydrolysis to fold a protein into a native state that is thermodynam...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6123477/ https://www.ncbi.nlm.nih.gov/pubmed/30181618 http://dx.doi.org/10.1038/s41598-018-31641-w |