Unimpaired Responses to Vaccination With Protein Antigen Plus Adjuvant in Mice With Kit-Independent Mast Cell Deficiency

Innate inflammatory responses are crucial for induction and regulation of T cell and antibody responses. Mast cell (MC)-deficient Kit mutant mice showed impaired adaptive immunity, suggesting that MCs provide essential adjuvant activities, and pharmacological MC activation was proposed as a new adju...

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Detalles Bibliográficos
Autores principales: Schubert, Nadja, Lisenko, Katharina, Auerbach, Christian, Weitzmann, Anke, Ghouse, Shanawaz Mohammed, Muhandes, Lina, Haase, Christa, Häring, Tobias, Schulze, Livia, Voehringer, David, Gunzer, Florian, Müller, Werner, Feyerabend, Thorsten B., Rodewald, Hans-Reimer, Dudeck, Anne, Roers, Axel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6123530/
https://www.ncbi.nlm.nih.gov/pubmed/30210490
http://dx.doi.org/10.3389/fimmu.2018.01870

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