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9-cis-Retinoic Acid and 1,25-dihydroxy Vitamin D3 Improve the Differentiation of Neural Stem Cells into Oligodendrocytes through the Inhibition of the Notch and Wnt Signaling Pathways

BACKGROUND: Differentiating oligodendrocyte precursor cells (OPCs) into oligodendrocytes could be improved by inhibiting signaling pathways such as Wnt and Notch. 9-cis-retinoic acid (9-cis-RA) and 1,25-dihydroxyvitamin D(3) (1,25[OH](2)D(3)) can ameliorate oligodendrogenesis. We investigated whethe...

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Detalles Bibliográficos
Autores principales: Saeb, Saeedeh, Azari, Hassan, Mostafavi-Pour, Zohreh, Ghanbari, Amir, Ebrahimi, Sepideh, Mokarram, Pooneh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Iranian Journal of Medical Sciences 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6123560/
https://www.ncbi.nlm.nih.gov/pubmed/30214105