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Towards understanding aromatase inhibitory activity via QSAR modeling

Aromatase is a rate-limiting enzyme for estrogen biosynthesis that is overproduced in breast cancer tissue. To block the growth of breast tumors, aromatase inhibitors (AIs) are employed to bind and inhibit aromatase in order to lower the amount of estrogen produced in the body. Although a number of...

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Detalles Bibliográficos
Autores principales:	Shoombuatong, Watshara, Schaduangrat, Nalini, Nantasenamat, Chanin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Leibniz Research Centre for Working Environment and Human Factors 2018
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6123608/ https://www.ncbi.nlm.nih.gov/pubmed/30190660 http://dx.doi.org/10.17179/excli2018-1417

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