Structural and functional studies of the metalloregulator Fur identify a promoter-binding mechanism and its role in Francisella tularensis virulence

Francisella tularensis is a Gram-negative bacterium causing tularaemia. Classified as possible bioterrorism agent, it may be transmitted to humans via animal infection or inhalation leading to severe pneumonia. Its virulence is related to iron homeostasis involving siderophore biosynthesis directly...

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Detalles Bibliográficos
Autores principales: Pérard, J., Nader, S., Levert, M., Arnaud, L., Carpentier, P., Siebert, C., Blanquet, F., Cavazza, C., Renesto, P., Schneider, D., Maurin, M., Coves, J., Crouzy, S., Michaud-Soret, I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6123631/
https://www.ncbi.nlm.nih.gov/pubmed/30271974
http://dx.doi.org/10.1038/s42003-018-0095-6

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