Effects of copper occupancy on the conformational landscape of peptidylglycine α-hydroxylating monooxygenase

The structures of metalloproteins that use redox-active metals for catalysis are usually exquisitely folded in a way that they are prearranged to accept their metal cofactors. Peptidylglycine α-hydroxylating monooxygenase (PHM) is a dicopper enzyme that catalyzes hydroxylation of the α-carbon of gly...

Descripción completa

Detalles Bibliográficos
Autores principales: Maheshwari, Sweta, Shimokawa, Chizu, Rudzka, Katarzyna, Kline, Chelsey D., Eipper, Betty A., Mains, Richard E., Gabelli, Sandra B., Blackburn, Ninian, Amzel, L. Mario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6123673/
https://www.ncbi.nlm.nih.gov/pubmed/30271955
http://dx.doi.org/10.1038/s42003-018-0082-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6123673/
https://www.ncbi.nlm.nih.gov/pubmed/30271955
http://dx.doi.org/10.1038/s42003-018-0082-y

Ejemplares similares