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Large conformational changes of a highly dynamic pre-protein binding domain in SecA

SecA is an essential molecular motor for the translocation of proteins across the membrane via the bacterial Sec secretion system. While the Sec system is found in all cells from archaea to multicellular eukaryotes, the SecA protein is mainly found in bacteria. The mechanism of how the motor protein...

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Detalles Bibliográficos
Autores principales: Ernst, Isabel, Haase, Maximilian, Ernst, Stefan, Yuan, Shuguang, Kuhn, Andreas, Leptihn, Sebastian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6123708/
https://www.ncbi.nlm.nih.gov/pubmed/30272009
http://dx.doi.org/10.1038/s42003-018-0133-4