Flagella-mediated secretion of a novel Vibrio cholerae cytotoxin affecting both vertebrate and invertebrate hosts

Using Caenorhabditis elegans as an infection host model for Vibrio cholerae predator interactions, we discovered a bacterial cytotoxin, MakA, whose function as a virulence factor relies on secretion via the flagellum channel in a proton motive force-dependent manner. The MakA protein is expressed fr...

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Detalles Bibliográficos
Autores principales: Dongre, Mitesh, Singh, Bhupender, Aung, Kyaw Min, Larsson, Per, Miftakhova, Regina, Persson, Karina, Askarian, Fatemeh, Johannessen, Mona, von Hofsten, Jonas, Persson, Jenny L., Erhardt, Marc, Tuck, Simon, Uhlin, Bernt Eric, Wai, Sun Nyunt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6123715/
https://www.ncbi.nlm.nih.gov/pubmed/30271941
http://dx.doi.org/10.1038/s42003-018-0065-z

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