Genome-wide somatic variant calling using localized colored de Bruijn graphs

Reliable detection of somatic variations is of critical importance in cancer research. Here we present Lancet, an accurate and sensitive somatic variant caller, which detects SNVs and indels by jointly analyzing reads from tumor and matched normal samples using colored de Bruijn graphs. We demonstra...

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Detalles Bibliográficos
Autores principales: Narzisi, Giuseppe, Corvelo, André, Arora, Kanika, Bergmann, Ewa A., Shah, Minita, Musunuri, Rajeeva, Emde, Anne-Katrin, Robine, Nicolas, Vacic, Vladimir, Zody, Michael C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6123722/
https://www.ncbi.nlm.nih.gov/pubmed/30271907
http://dx.doi.org/10.1038/s42003-018-0023-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6123722/
https://www.ncbi.nlm.nih.gov/pubmed/30271907
http://dx.doi.org/10.1038/s42003-018-0023-9

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