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A Zeb2-miR-200c loop controls midbrain dopaminergic neuron neurogenesis and migration

Zeb2 is a homeodomain transcription factor that plays pleiotropic functions during embryogenesis, but its role for midbrain dopaminergic (mDA) neuron development is unknown. Here we report that Zeb2 is highly expressed in progenitor cells in the ventricular zone of the midbrain floor plate and downr...

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Detalles Bibliográficos
Autores principales: Yang, Shanzheng, Toledo, Enrique M., Rosmaninho, Pedro, Peng, Changgeng, Uhlén, Per, Castro, Diogo S., Arenas, Ernest
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6123725/
https://www.ncbi.nlm.nih.gov/pubmed/30271956
http://dx.doi.org/10.1038/s42003-018-0080-0