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A Zeb2-miR-200c loop controls midbrain dopaminergic neuron neurogenesis and migration
Zeb2 is a homeodomain transcription factor that plays pleiotropic functions during embryogenesis, but its role for midbrain dopaminergic (mDA) neuron development is unknown. Here we report that Zeb2 is highly expressed in progenitor cells in the ventricular zone of the midbrain floor plate and downr...
Autores principales: | Yang, Shanzheng, Toledo, Enrique M., Rosmaninho, Pedro, Peng, Changgeng, Uhlén, Per, Castro, Diogo S., Arenas, Ernest |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6123725/ https://www.ncbi.nlm.nih.gov/pubmed/30271956 http://dx.doi.org/10.1038/s42003-018-0080-0 |
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