In situ serial crystallography for rapid de novo membrane protein structure determination

De novo membrane protein structure determination is often limited by the availability of large crystals and the difficulties in obtaining accurate diffraction data for experimental phasing. Here we present a method that combines in situ serial crystallography with de novo phasing for fast, efficient...

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Detalles Bibliográficos
Autores principales: Huang, Chia-Ying, Olieric, Vincent, Howe, Nicole, Warshamanage, Rangana, Weinert, Tobias, Panepucci, Ezequiel, Vogeley, Lutz, Basu, Shibom, Diederichs, Kay, Caffrey, Martin, Wang, Meitian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6123769/
https://www.ncbi.nlm.nih.gov/pubmed/30272004
http://dx.doi.org/10.1038/s42003-018-0123-6

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