Limbic and new onset refractory tonic status epilepticus (NORSE) in anti-NMDAR encephalitis()

AIMS: To present a case of anti-NMDA receptor encephalitis (anti-NMDAR) with new onset refractory non-convulsive status epilepticus (NORSE). METHODS: Case report with clinical details, MRI, PET, and EEG illustrations. RESULTS: New onset refractory status epilepticus (NORSE) may arise from anti-NMDAR...

Descripción completa

Detalles Bibliográficos
Autores principales: Kaplan, Peter W., Probasco, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Clinical and Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6123859/
https://www.ncbi.nlm.nih.gov/pubmed/30214986
http://dx.doi.org/10.1016/j.cnp.2017.06.003
_version_ 1783352917400485888
author Kaplan, Peter W.
Probasco, John
author_facet Kaplan, Peter W.
Probasco, John
author_sort Kaplan, Peter W.
collection PubMed
description AIMS: To present a case of anti-NMDA receptor encephalitis (anti-NMDAR) with new onset refractory non-convulsive status epilepticus (NORSE). METHODS: Case report with clinical details, MRI, PET, and EEG illustrations. RESULTS: New onset refractory status epilepticus (NORSE) may arise from anti-NMDAR, and offers diagnostic and treatment challenges for immuno-therapy and refractory status epilepticus. Non-convulsive status epilepticus with generalized fast activity, has not been reported in anti-NMDAR, in NORSE. CONCLUSIONS: A patient with anti-NMDAR and generalized status with stiffening, right focal weakness, high frequency alpha/beta on EEG, brain FDG-PET/CT changes in the left temporo-parietal regions and cerebellum was presented. We discuss the unique treatment challenges of anti-NMDAR. NORSE and generalized nonconvulsive status epilepticus.
format Online
Article
Text
id pubmed-6123859
institution National Center for Biotechnology Information
language English
publishDate 2017
publisher Elsevier
record_format MEDLINE/PubMed
spelling pubmed-61238592018-09-13 Limbic and new onset refractory tonic status epilepticus (NORSE) in anti-NMDAR encephalitis() Kaplan, Peter W. Probasco, John Clin Neurophysiol Pract Clinical and Research Article AIMS: To present a case of anti-NMDA receptor encephalitis (anti-NMDAR) with new onset refractory non-convulsive status epilepticus (NORSE). METHODS: Case report with clinical details, MRI, PET, and EEG illustrations. RESULTS: New onset refractory status epilepticus (NORSE) may arise from anti-NMDAR, and offers diagnostic and treatment challenges for immuno-therapy and refractory status epilepticus. Non-convulsive status epilepticus with generalized fast activity, has not been reported in anti-NMDAR, in NORSE. CONCLUSIONS: A patient with anti-NMDAR and generalized status with stiffening, right focal weakness, high frequency alpha/beta on EEG, brain FDG-PET/CT changes in the left temporo-parietal regions and cerebellum was presented. We discuss the unique treatment challenges of anti-NMDAR. NORSE and generalized nonconvulsive status epilepticus. Elsevier 2017-07-01 /pmc/articles/PMC6123859/ /pubmed/30214986 http://dx.doi.org/10.1016/j.cnp.2017.06.003 Text en © 2017 International Federation of Clinical Neurophysiology. Published by Elsevier B.V. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Clinical and Research Article
Kaplan, Peter W.
Probasco, John
Limbic and new onset refractory tonic status epilepticus (NORSE) in anti-NMDAR encephalitis()
title Limbic and new onset refractory tonic status epilepticus (NORSE) in anti-NMDAR encephalitis()
title_full Limbic and new onset refractory tonic status epilepticus (NORSE) in anti-NMDAR encephalitis()
title_fullStr Limbic and new onset refractory tonic status epilepticus (NORSE) in anti-NMDAR encephalitis()
title_full_unstemmed Limbic and new onset refractory tonic status epilepticus (NORSE) in anti-NMDAR encephalitis()
title_short Limbic and new onset refractory tonic status epilepticus (NORSE) in anti-NMDAR encephalitis()
title_sort limbic and new onset refractory tonic status epilepticus (norse) in anti-nmdar encephalitis()
topic Clinical and Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6123859/
https://www.ncbi.nlm.nih.gov/pubmed/30214986
http://dx.doi.org/10.1016/j.cnp.2017.06.003
work_keys_str_mv AT kaplanpeterw limbicandnewonsetrefractorytonicstatusepilepticusnorseinantinmdarencephalitis
AT probascojohn limbicandnewonsetrefractorytonicstatusepilepticusnorseinantinmdarencephalitis

Ejemplares similares