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Initial B Cell Activation Induces Metabolic Reprogramming and Mitochondrial Remodeling

B lymphocytes provide adaptive immunity by generating antigen-specific antibodies and supporting the activation of T cells. Little is known about how global metabolism supports naive B cell activation to enable an effective immune response. By coupling RNA sequencing (RNA-seq) data with glucose isot...

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Detalles Bibliográficos
Autores principales:	Waters, Lynnea R., Ahsan, Fasih M., Wolf, Dane M., Shirihai, Orian, Teitell, Michael A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6123864/ https://www.ncbi.nlm.nih.gov/pubmed/30240649 http://dx.doi.org/10.1016/j.isci.2018.07.005

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