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Downregulation of hypermethylated in cancer-1 by miR-4532 promotes adriamycin resistance in breast cancer cells

BACKGROUND: MicroRNAs are small RNAs (~ 22 nt) that modulate the expression of thousands of genes in tumors and play important roles in the formation of multidrug resistance. In this study, we firstly investigated that miR-4532 involved in the multidrug resistance formation of breast cancer by targe...

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Detalles Bibliográficos
Autores principales: Feng, Fan, Zhu, Xiaolan, Wang, Chunyan, Chen, Liang, Cao, Weiping, Liu, Yueqin, Chen, Qi, Xu, Wenlin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6123967/
https://www.ncbi.nlm.nih.gov/pubmed/30202238
http://dx.doi.org/10.1186/s12935-018-0616-x