Association of cough hypersensitivity with tracheal TRPV1 activation and neurogenic inflammation in a novel guinea pig model of citric acid-induced chronic cough

OBJECTIVE: This study was performed to establish a novel model of citric acid-induced chronic cough in guinea pigs and to investigate the pathogenesis of cough hypersensitivity. METHODS: Healthy conscious guinea pigs inhaled citric acid (0.4 M) for 3 minutes twice daily for 25 days. Cough reactivity...

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Detalles Bibliográficos
Autores principales: Xu, Xianghuai, Chen, Qiang, Qiu, Zhongmin, Shi, Cuiqin, Ding, Hongmei, Wang, Lan, Lv, Hanjing, Yu, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2018
Materias:
Pre-Clinical Research Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6124251/
https://www.ncbi.nlm.nih.gov/pubmed/29877121
http://dx.doi.org/10.1177/0300060518778951

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6124251/
https://www.ncbi.nlm.nih.gov/pubmed/29877121
http://dx.doi.org/10.1177/0300060518778951

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