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Sevoflurane exerts brain-protective effects against sepsis-associated encephalopathy and memory impairment through caspase 3/9 and Bax/Bcl signaling pathway in a rat model of sepsis
OBJECTIVE: We compared the effects of sevoflurane and isoflurane on systemic inflammation, sepsis-associated encephalopathy, and memory impairment in a rat sepsis model of cecal ligation and puncture (CLP)-induced polymicrobial peritonitis. METHODS: Twenty-four rats were assigned to sham, CLP, CLP +...
Autores principales: | Bedirli, Nurdan, Bagriacik, Emin Umit, Yilmaz, Guldal, Ozkose, Zerrin, Kavutçu, Mustafa, Cavunt Bayraktar, Aslı, Bedirli, Abdulkadir |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6124281/ https://www.ncbi.nlm.nih.gov/pubmed/29756489 http://dx.doi.org/10.1177/0300060518773265 |
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