Cargando…

WW domain-containing E3 ubiquitin protein ligase 1 depletion evokes antitumor effect in cutaneous squamous cell carcinoma by inhibiting signal transducer and activator of transcription 3 signaling pathway

OBJECTIVES: WW domain-containing E3 ubiquitin protein ligase 1 (WWP1) has been implicated in tumor progression. We aimed to investigate the role of WWP1 in cutaneous squamous cell carcinoma (CSCC). METHODS: WWP1 gene and protein levels were detected using semi-quantitative reverse transcription-poly...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xia, Yonghua, Chang, Xiao, Lian, Shi, Zhu, Wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	SAGE Publications 2018
Materias:	Pre-Clinical Research Reports
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6124284/ https://www.ncbi.nlm.nih.gov/pubmed/29888632 http://dx.doi.org/10.1177/0300060518778905

Ejemplares similares

Correlation of signal transducer and activator of transcription-3 and β-catenin expression in laryngeal squamous cell carcinoma
por: Sun, Yajing, et al.
Publicado: (2023)

Inhibition of protease-activated receptor-2 induces apoptosis in cervical cancer by inhibiting signal transducer and activator of transcription-3 signaling
por: Shanshan, Hu, et al.
Publicado: (2019)

Smad7 Binds Differently to Individual and Tandem WW3 and WW4 Domains of WWP2 Ubiquitin Ligase Isoforms
por: Wahl, Lloyd C., et al.
Publicado: (2019)

WW Domain-Containing E3 Ubiquitin Protein Ligase 1: A Self-Disciplined Oncoprotein
por: Kuang, Linghan, et al.
Publicado: (2021)

E3 ubiquitin ligases in the acute leukemic signaling pathways
por: Zhan, Qianru, et al.
Publicado: (2022)

Inhibitors of cullin-RING E3 ubiquitin ligase 4 with antitumor potential
por: Wu, Kenneth, et al.
Publicado: (2021)

Regulation of Hippo/YAP signaling and Esophageal Squamous Carcinoma progression by an E3 ubiquitin ligase PARK2
por: Zhou, Xiaofeng, et al.
Publicado: (2020)

Role of WW domain E3 ubiquitin protein ligase 2 in modulating ubiquitination and Degradation of Septin4 in oxidative stress endothelial injury
por: Zhang, Naijin, et al.
Publicado: (2020)

Substrate clustering potently regulates the activity of WW-HECT domain–containing ubiquitin ligases
por: Mund, Thomas, et al.
Publicado: (2018)

The role of Src homology region 2 domain-containing phosphatase-1 hypermethylation in the classification of patients with myelodysplastic syndromes and its association with signal transducer and activator of transcription 3 phosphorylation in skm-1 cells
por: Han, Ying, et al.
Publicado: (2021)

Shutdown of interferon signaling by a viral-hijacked E3 ubiquitin ligase
por: Davis, Kaitlin A., et al.
Publicado: (2017)

Structural Plasticity of D3-D14 Ubiquitin Ligase in Strigolactone Signaling
por: Shabek, Nitzan, et al.
Publicado: (2018)

Negative regulation of NEMO signaling by the ubiquitin E3 ligase MARCH2
por: Chathuranga, Kiramage, et al.
Publicado: (2020)

Signaling-mediated control of ubiquitin ligases in endocytosis
por: Polo, Simona
Publicado: (2012)

Control of TGFβ signalling by ubiquitination independent function of E3 ubiquitin ligase TRIP12
por: Keyan, Kripa S, et al.
Publicado: (2023)

Control of the dynamics and homeostasis of the Drosophila Hedgehog receptor Patched by two C2-WW-HECT-E3 Ubiquitin ligases
por: Brigui, Amira, et al.
Publicado: (2015)

MAVS recruits multiple ubiquitin E3 ligases to activate antiviral signaling cascades
por: Liu, Siqi, et al.
Publicado: (2013)

E3 Ubiquitin Ligases: Key Regulators of TGFβ Signaling in Cancer Progression
por: Sinha, Abhishek, et al.
Publicado: (2021)

The E3 ubiquitin ligase component, Cereblon, is an evolutionarily conserved regulator of Wnt signaling
por: Shen, Chen, et al.
Publicado: (2021)

S-Nitrosation of E3 Ubiquitin Ligase Complex Components Regulates Hormonal Signalings in Arabidopsis
por: Terrile, Maria Cecilia, et al.
Publicado: (2022)

Dihydroartemisinin inhibits IL-6-induced epithelial–mesenchymal transition in laryngeal squamous cell carcinoma via the miR-130b-3p/STAT3/β-catenin signaling pathway
por: Sun, Yajing, et al.
Publicado: (2021)

Itch E3 Ubiquitin Ligase Positively Regulates TGF-β Signaling to EMT via Smad7 Ubiquitination
por: Park, Su-hyun, et al.
Publicado: (2015)

Molecular Interactions between Two LMP2A PY Motifs of EBV and WW Domains of E3 Ubiquitin Ligase AIP4
por: Seo, Min-Duk, et al.
Publicado: (2021)

E3 ubiquitin ligases and deubiquitinases as modulators of TRAIL-mediated extrinsic apoptotic signaling pathway
por: Woo, Seon Min, et al.
Publicado: (2019)

Role of RING-Type E3 Ubiquitin Ligases in Inflammatory Signalling and Inflammatory Bowel Disease
por: Zhu, Liguo, et al.
Publicado: (2020)

Regulation of P53 signaling in breast cancer by the E3 ubiquitin ligase RNF187
por: Li, Xin, et al.
Publicado: (2022)

How the ends signal the end: Regulation by E3 ubiquitin ligases recognizing protein termini
por: Sherpa, Dawafuti, et al.
Publicado: (2022)

Antitumor activity of a novel oral signal transducer and activator of transcription 3 inhibitor YHO‐1701
por: Nishisaka, Fukiko, et al.
Publicado: (2020)

Corosolic acid enhances the antitumor effects of chemotherapy on epithelial ovarian cancer by inhibiting signal transducer and activator of transcription 3 signaling
por: FUJIWARA, YUKIO, et al.
Publicado: (2013)

Regulation of MAPK Signaling Pathways by the Large HERC Ubiquitin Ligases
por: Sala-Gaston, Joan, et al.
Publicado: (2023)

The Ubiquitin Ligase TRAF6 Negatively Regulates the JAK-STAT Signaling Pathway by Binding to STAT3 and Mediating Its Ubiquitination
por: Wei, Juncheng, et al.
Publicado: (2012)

AIRE Functions As an E3 Ubiquitin Ligase
por: Uchida, Daisuke, et al.
Publicado: (2004)

Structural Diversity of Ubiquitin E3 Ligase
por: Toma-Fukai, Sachiko, et al.
Publicado: (2021)

Nelfinavir restricts A549 cell growth by inhibiting STAT3 signaling
por: He, Fangli, et al.
Publicado: (2021)

The E3 ligase TRAF4 promotes IGF signaling by mediating atypical ubiquitination of IRS-1
por: Yu, Wenjuan, et al.
Publicado: (2021)

The E3 ubiquitin ligase MG53 inhibits hepatocellular carcinoma by targeting RAC1 signaling
por: Ma, Xiaomin, et al.
Publicado: (2022)

Melatonin attenuates AFB1-induced cardiotoxicity via the NLRP3 signalling pathway
por: Yan, Hui, et al.
Publicado: (2020)

Mechanism of Cullin3 E3 Ubiquitin Ligase Dimerization
por: Choo, Yin Yin, et al.
Publicado: (2012)

Kinectin1 depletion promotes EGFR degradation via the ubiquitin-proteosome system in cutaneous squamous cell carcinoma
por: Ma, Ji, et al.
Publicado: (2021)

NEDD4 E3 ubiquitin protein ligase serves an important role in cutaneous melanoma occurrence and development
por: Cheng, Fang, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_l9almgb3664jq1it9o85i5uihq