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Lens-specific deletion of the Msx2 gene increased apoptosis by enhancing the caspase-3/caspase-8 signaling pathway

OBJECTIVE: To investigate the influence of Msx2 conditional gene knockout during lens development in mice. METHODS: Lens-specific Msx2 knockout mice were generated using the Cre-loxP system. The eyes of Msx2 conditional knockout (Msx2CKO) and wild-type (Msx2WT) mice were examined during embryonic an...

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Detalles Bibliográficos
Autores principales:	Yu, Ziyan, Yu, Wenting, Liu, Jia, Wu, Danhong, Wang, Chunxia, Zhang, Jinsong, Zhao, Jiangyue
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	SAGE Publications 2018
Materias:	Pre-Clinical Research Reports
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6124292/ https://www.ncbi.nlm.nih.gov/pubmed/29921154 http://dx.doi.org/10.1177/0300060518774687

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