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Low-dose hydroxycarbamide therapy may offer similar benefit as maximum tolerated dose for children and young adults with sickle cell disease in low-middle-income settings

The multiple clinical benefits of hydroxycarbamide in sickle cell disease are supported by a large body of evidence. The maximum tolerated dose (MTD) is the regimen recommended by guidelines from a panel of National Heart, Lung, and Blood Institute (NHLBI) experts, but other dosage regimens have bee...

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Detalles Bibliográficos
Autores principales:	Inusa, Baba Psalm Duniya, Atoyebi, Wale, Hassan, Abdul Aziz, Idhate, Tushar, Dogara, Livingstone, Ijei, Ifeoma, Qin, Yewen, Anie, Kofi, Lawson, Juliana Olufunke, Hsu, Lewis
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	F1000 Research Limited 2018
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6124375/ https://www.ncbi.nlm.nih.gov/pubmed/30228870 http://dx.doi.org/10.12688/f1000research.14589.1

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