Analysis of the complete genome of hepatitis B virus subgenotype C2 isolate NHB17965 from a HBV infected patient

The burden of chronic hepatitis B virus (HBV) infections is increasingly detected nowadays. Herein, we report a complete genome of HBV subgenotype C2 (HBV/C2) from a HBV infected patient. Complete genome analysis revealed that the isolated strain was a non-recombinant wild type and had several regul...

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Detalles Bibliográficos
Autores principales: Shaha, Modhusudon, Sarker, Palash Kumar, Hossain, Md. Saddam, Das, Keshob Chandra, Jahan, Munira, Dey, Shuvra Kanti, Tabassum, Shahina, Hashem, Abu, Salimullah, Md.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2018
Materias:
Research Note
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6124380/
https://www.ncbi.nlm.nih.gov/pubmed/30228877
http://dx.doi.org/10.12688/f1000research.15090.3
Descripción
Sumario:The burden of chronic hepatitis B virus (HBV) infections is increasingly detected nowadays. Herein, we report a complete genome of HBV subgenotype C2 (HBV/C2) from a HBV infected patient. Complete genome analysis revealed that the isolated strain was a non-recombinant wild type and had several regular substitutions in the reverse transcriptase domain and small surface proteins of HBV. This study may help clinicians and scientists gain in-depth knowledge on the current substitutions of HBV/C2 genome and to identify potential therapies against HBV infections.

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