Analysis of the complete genome of hepatitis B virus subgenotype C2 isolate NHB17965 from a HBV infected patient

The burden of chronic hepatitis B virus (HBV) infections is increasingly detected nowadays. Herein, we report a complete genome of HBV subgenotype C2 (HBV/C2) from a HBV infected patient. Complete genome analysis revealed that the isolated strain was a non-recombinant wild type and had several regul...

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Autores principales: Shaha, Modhusudon, Sarker, Palash Kumar, Hossain, Md. Saddam, Das, Keshob Chandra, Jahan, Munira, Dey, Shuvra Kanti, Tabassum, Shahina, Hashem, Abu, Salimullah, Md.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2018
Materias:
Research Note
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6124380/
https://www.ncbi.nlm.nih.gov/pubmed/30228877
http://dx.doi.org/10.12688/f1000research.15090.3
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author Shaha, Modhusudon
Sarker, Palash Kumar
Hossain, Md. Saddam
Das, Keshob Chandra
Jahan, Munira
Dey, Shuvra Kanti
Tabassum, Shahina
Hashem, Abu
Salimullah, Md.
author_facet Shaha, Modhusudon
Sarker, Palash Kumar
Hossain, Md. Saddam
Das, Keshob Chandra
Jahan, Munira
Dey, Shuvra Kanti
Tabassum, Shahina
Hashem, Abu
Salimullah, Md.
author_sort Shaha, Modhusudon
collection PubMed
description The burden of chronic hepatitis B virus (HBV) infections is increasingly detected nowadays. Herein, we report a complete genome of HBV subgenotype C2 (HBV/C2) from a HBV infected patient. Complete genome analysis revealed that the isolated strain was a non-recombinant wild type and had several regular substitutions in the reverse transcriptase domain and small surface proteins of HBV. This study may help clinicians and scientists gain in-depth knowledge on the current substitutions of HBV/C2 genome and to identify potential therapies against HBV infections.
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spelling pubmed-61243802018-09-17 Analysis of the complete genome of hepatitis B virus subgenotype C2 isolate NHB17965 from a HBV infected patient Shaha, Modhusudon Sarker, Palash Kumar Hossain, Md. Saddam Das, Keshob Chandra Jahan, Munira Dey, Shuvra Kanti Tabassum, Shahina Hashem, Abu Salimullah, Md. F1000Res Research Note The burden of chronic hepatitis B virus (HBV) infections is increasingly detected nowadays. Herein, we report a complete genome of HBV subgenotype C2 (HBV/C2) from a HBV infected patient. Complete genome analysis revealed that the isolated strain was a non-recombinant wild type and had several regular substitutions in the reverse transcriptase domain and small surface proteins of HBV. This study may help clinicians and scientists gain in-depth knowledge on the current substitutions of HBV/C2 genome and to identify potential therapies against HBV infections. F1000 Research Limited 2018-09-10 /pmc/articles/PMC6124380/ /pubmed/30228877 http://dx.doi.org/10.12688/f1000research.15090.3 Text en Copyright: © 2018 Shaha M et al. http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Note
Shaha, Modhusudon
Sarker, Palash Kumar
Hossain, Md. Saddam
Das, Keshob Chandra
Jahan, Munira
Dey, Shuvra Kanti
Tabassum, Shahina
Hashem, Abu
Salimullah, Md.
Analysis of the complete genome of hepatitis B virus subgenotype C2 isolate NHB17965 from a HBV infected patient
title Analysis of the complete genome of hepatitis B virus subgenotype C2 isolate NHB17965 from a HBV infected patient
title_full Analysis of the complete genome of hepatitis B virus subgenotype C2 isolate NHB17965 from a HBV infected patient
title_fullStr Analysis of the complete genome of hepatitis B virus subgenotype C2 isolate NHB17965 from a HBV infected patient
title_full_unstemmed Analysis of the complete genome of hepatitis B virus subgenotype C2 isolate NHB17965 from a HBV infected patient
title_short Analysis of the complete genome of hepatitis B virus subgenotype C2 isolate NHB17965 from a HBV infected patient
title_sort analysis of the complete genome of hepatitis b virus subgenotype c2 isolate nhb17965 from a hbv infected patient
topic Research Note
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6124380/
https://www.ncbi.nlm.nih.gov/pubmed/30228877
http://dx.doi.org/10.12688/f1000research.15090.3
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