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Distinct prophase arrest mechanisms in human male meiosis
To prevent chromosomal aberrations being transmitted to the offspring, strict meiotic checkpoints are in place to remove aberrant spermatocytes. However, in about 1% of males these checkpoints cause complete meiotic arrest leading to azoospermia and subsequent infertility. Here, we unravel two clear...
Autores principales: | Jan, Sabrina Z., Jongejan, Aldo, Korver, Cindy M., van Daalen, Saskia K. M., van Pelt, Ans M. M., Repping, Sjoerd, Hamer, Geert |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6124541/ https://www.ncbi.nlm.nih.gov/pubmed/29540502 http://dx.doi.org/10.1242/dev.160614 |
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