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Biochemical and histological evidence of deteriorated bioprosthetic valve leaflets: the accumulation of fibrinogen and plasminogen

Calcification of bioprosthetic valves (BVs) implanted in aortic position can result in gradual deterioration and necessitate aortic valve replacement. The molecular mechanism of calcium deposition on BV leaflets has been investigated, but remains to be fully elucidated. The present study aimed to id...

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Detalles Bibliográficos
Autores principales:	Sakaue, Tomohisa, Nakaoka, Hirotomo, Shikata, Fumiaki, Aono, Jun, Kurata, Mie, Uetani, Teruyoshi, Hamaguchi, Mika, Kojima, Ai, Uchita, Shunji, Yasugi, Takumi, Higashi, Haruhiko, Suzuki, Jun, Ikeda, Shuntaro, Higaki, Jitsuo, Higashiyama, Shigeki, Izutani, Hironori
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Company of Biologists Ltd 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6124578/ https://www.ncbi.nlm.nih.gov/pubmed/30089611 http://dx.doi.org/10.1242/bio.034009

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