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Using structural equation modelling to jointly estimate maternal and fetal effects on birthweight in the UK Biobank

BACKGROUND: To date, 60 genetic variants have been robustly associated with birthweight. It is unclear whether these associations represent the effect of an individual’s own genotype on their birthweight, their mother’s genotype, or both. METHODS: We demonstrate how structural equation modelling (SE...

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Detalles Bibliográficos
Autores principales: Warrington, Nicole M, Freathy, Rachel M, Neale, Michael C, Evans, David M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6124616/
https://www.ncbi.nlm.nih.gov/pubmed/29447406
http://dx.doi.org/10.1093/ije/dyy015