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Using structural equation modelling to jointly estimate maternal and fetal effects on birthweight in the UK Biobank
BACKGROUND: To date, 60 genetic variants have been robustly associated with birthweight. It is unclear whether these associations represent the effect of an individual’s own genotype on their birthweight, their mother’s genotype, or both. METHODS: We demonstrate how structural equation modelling (SE...
Autores principales: | Warrington, Nicole M, Freathy, Rachel M, Neale, Michael C, Evans, David M |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6124616/ https://www.ncbi.nlm.nih.gov/pubmed/29447406 http://dx.doi.org/10.1093/ije/dyy015 |
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