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Reference values for body composition and associations with blood pressure in Kenyan adults aged ≥50 years old
BACKGROUND/OBJECTIVES: To develop age- and sex-specific centile reference curves for fat-free mass (FFM) and fat mass (FM) adjusted for height in an adult Kenyan population and to investigate the association between FM, FFM and blood pressure (BP). SUBJECTS/METHODS: Measures of body composition from...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6124645/ https://www.ncbi.nlm.nih.gov/pubmed/29769749 http://dx.doi.org/10.1038/s41430-018-0177-z |
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author | Bastawrous, Madeleine C. Piernas, Carmen Bastawrous, Andrew Oke, Jason Lasserson, Daniel Mathenge, Wanjiku Burton, Matthew J. Jebb, Susan A. Kuper, Hannah |
author_facet | Bastawrous, Madeleine C. Piernas, Carmen Bastawrous, Andrew Oke, Jason Lasserson, Daniel Mathenge, Wanjiku Burton, Matthew J. Jebb, Susan A. Kuper, Hannah |
author_sort | Bastawrous, Madeleine C. |
collection | PubMed |
description | BACKGROUND/OBJECTIVES: To develop age- and sex-specific centile reference curves for fat-free mass (FFM) and fat mass (FM) adjusted for height in an adult Kenyan population and to investigate the association between FM, FFM and blood pressure (BP). SUBJECTS/METHODS: Measures of body composition from bioimpedance analyses and BP were collected in 1995 participants aged ≥50 years in Nakuru County, Kenya. Reference curves were produced using the LMS method. Multivariable linear regression models were used to test the cross-sectional association between body composition indexes and BP. RESULTS: The age- and sex-specific reference curves for body composition (FMI and FFMI) confirmed that FFMI is lower in both men and women with increasing age. FMI declines with age in women while among men the decline starts after 70 years. FFM was higher in men (47.4 ± 7.2 kg) than in women (38.8 ± 5.5 kg), while FM was lower in men (17.3 ± 8.1 kg) than in women (24.4 ± 10.2 kg). FMI, FFMI and BMI were all positively associated with systolic and diastolic BP, and after adjusting for body weight, FFMI remained positively associated with systolic BP and the FMI remained positively associated with diastolic BP. There was no evidence to suggest that FMI and FFMI were superior to measurement of BMI alone. CONCLUSIONS: These body composition reference curves provide normative data on body composition for older adults in Kenya. Further research should consider the prospective associations with health, including frailty-related outcomes. |
format | Online Article Text |
id | pubmed-6124645 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-61246452018-11-15 Reference values for body composition and associations with blood pressure in Kenyan adults aged ≥50 years old Bastawrous, Madeleine C. Piernas, Carmen Bastawrous, Andrew Oke, Jason Lasserson, Daniel Mathenge, Wanjiku Burton, Matthew J. Jebb, Susan A. Kuper, Hannah Eur J Clin Nutr Article BACKGROUND/OBJECTIVES: To develop age- and sex-specific centile reference curves for fat-free mass (FFM) and fat mass (FM) adjusted for height in an adult Kenyan population and to investigate the association between FM, FFM and blood pressure (BP). SUBJECTS/METHODS: Measures of body composition from bioimpedance analyses and BP were collected in 1995 participants aged ≥50 years in Nakuru County, Kenya. Reference curves were produced using the LMS method. Multivariable linear regression models were used to test the cross-sectional association between body composition indexes and BP. RESULTS: The age- and sex-specific reference curves for body composition (FMI and FFMI) confirmed that FFMI is lower in both men and women with increasing age. FMI declines with age in women while among men the decline starts after 70 years. FFM was higher in men (47.4 ± 7.2 kg) than in women (38.8 ± 5.5 kg), while FM was lower in men (17.3 ± 8.1 kg) than in women (24.4 ± 10.2 kg). FMI, FFMI and BMI were all positively associated with systolic and diastolic BP, and after adjusting for body weight, FFMI remained positively associated with systolic BP and the FMI remained positively associated with diastolic BP. There was no evidence to suggest that FMI and FFMI were superior to measurement of BMI alone. CONCLUSIONS: These body composition reference curves provide normative data on body composition for older adults in Kenya. Further research should consider the prospective associations with health, including frailty-related outcomes. Nature Publishing Group UK 2018-05-15 2019 /pmc/articles/PMC6124645/ /pubmed/29769749 http://dx.doi.org/10.1038/s41430-018-0177-z Text en © The Author(s) 2018 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Article Bastawrous, Madeleine C. Piernas, Carmen Bastawrous, Andrew Oke, Jason Lasserson, Daniel Mathenge, Wanjiku Burton, Matthew J. Jebb, Susan A. Kuper, Hannah Reference values for body composition and associations with blood pressure in Kenyan adults aged ≥50 years old |
title | Reference values for body composition and associations with blood pressure in Kenyan adults aged ≥50 years old |
title_full | Reference values for body composition and associations with blood pressure in Kenyan adults aged ≥50 years old |
title_fullStr | Reference values for body composition and associations with blood pressure in Kenyan adults aged ≥50 years old |
title_full_unstemmed | Reference values for body composition and associations with blood pressure in Kenyan adults aged ≥50 years old |
title_short | Reference values for body composition and associations with blood pressure in Kenyan adults aged ≥50 years old |
title_sort | reference values for body composition and associations with blood pressure in kenyan adults aged ≥50 years old |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6124645/ https://www.ncbi.nlm.nih.gov/pubmed/29769749 http://dx.doi.org/10.1038/s41430-018-0177-z |
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