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Generation and selection of pluripotent stem cells for robust differentiation to insulin-secreting cells capable of reversing diabetes in rodents

Induced pluripotent stem cell (iPSC) technology enables the creation and selection of pluripotent cells with specific genetic traits. This report describes a pluripotent cell line created specifically to form replacement pancreatic cells as a therapy for insulin-dependent diabetes. Beginning with pr...

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Detalles Bibliográficos
Autores principales: Southard, Sheryl M., Kotipatruni, Rama P., Rust, William L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6124757/
https://www.ncbi.nlm.nih.gov/pubmed/30183752
http://dx.doi.org/10.1371/journal.pone.0203126