A gene co-expression module implicating the mitochondrial electron transport chain is associated with long-term response to lithium treatment in bipolar affective disorder

Lithium is the first-line treatment for bipolar affective disorder (BPAD) but two-thirds of patients respond only partially or not at all. The reasons for this high variability in lithium response are not well understood. Transcriptome-wide profiling, which tests the interface between genes and the...

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Detalles Bibliográficos
Autores principales: Stacey, David, Schubert, K. Oliver, Clark, Scott R., Amare, Azmeraw T., Milanesi, Elena, Maj, Carlo, Leckband, Susan G., Shekhtman, Tatyana, Kelsoe, John R., Gurwitz, David, Baune, Bernhard T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6125294/
https://www.ncbi.nlm.nih.gov/pubmed/30185780
http://dx.doi.org/10.1038/s41398-018-0237-0

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