Cargando…

ATF3 Stimulates IL-17A by Regulating Intracellular Ca(2+)/ROS-Dependent IL-1β Activation During Streptococcus pneumoniae Infection

Activating transcription factor-3 (ATF3) in the ER stress pathway induces cytokine production and promotes survival during gram-positive bacterial infection. IL-17A is a critical cytokine that is essential for clearance of Streptococcus pneumoniae. However, the mechanism by which ATF3 induces IL-17A...

Descripción completa

Detalles Bibliográficos
Autores principales: Lee, Seungyeop, Kim, Gyu-Lee, Kim, Na Young, Kim, Se-Jin, Ghosh, Prachetash, Rhee, Dong-Kwon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6125349/
https://www.ncbi.nlm.nih.gov/pubmed/30214444
http://dx.doi.org/10.3389/fimmu.2018.01954