Cargando…

Expression profiling of ubiquitin-related genes in LKB1 mutant lung adenocarcinoma

Liver kinase B1 (LKB1) is a tumor suppressor, and there is a very high proportion of LKB1 mutation in lung adenocarcinoma. The function of LKB1 is closely related to that of ubiquitin related genes. Our objective is to analyze the changes in ubiquitin-related genes in LKB1 mutant lung adenocarcinoma...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Guanghui, Bie, Fenglong, Qu, Xiao, Yang, Xudong, Liu, Shaorui, Wang, Yu, Huang, Cuicui, Wang, Kai, Du, Jiajun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6125361/ https://www.ncbi.nlm.nih.gov/pubmed/30185829 http://dx.doi.org/10.1038/s41598-018-31592-2

Ejemplares similares

Tripartite motif-containing 15 overexpression in non-small cell lung cancer is associated with poor patient prognoses
por: Han, Xiaoying, et al.
Publicado: (2019)

The Prognostic Model and Drug Sensitivity of LKB1-Mutant Lung Adenocarcinoma Based on Immune Landscape
por: Wang, Guanghui, et al.
Publicado: (2022)

Appropriate surgical modalities for stages T2a and T2b in the eighth TNM classification of lung cancer
por: Bie, Fenglong, et al.
Publicado: (2017)

The Prognostic Significance of Pure Ground Glass Opacities in Lung Cancer Computed Tomographic Images
por: Huang, Cuicui, et al.
Publicado: (2019)

Mining and validating the expression pattern and prognostic value of acetylcholine receptors in non-small cell lung cancer
por: Ma, Guoyuan, et al.
Publicado: (2019)

Wedge resection is equal to segmental resection for pulmonary typical carcinoid patients at localized stage: a population-based analysis
por: Yan, Tao, et al.
Publicado: (2019)

A subset of VEGFR‐TKIs activates AMPK in LKB1‐mutant lung cancer
por: Yang, Lujie, et al.
Publicado: (2022)

Comprehensive analysis of suppressor of cytokine signaling 2 protein in the malignant transformation of NSCLC
por: Ma, Guoyuan, et al.
Publicado: (2023)

Prognostic value of IGF-1R in lung cancer: A PRISMA-compliant meta-analysis
por: Xu, Jun, et al.
Publicado: (2019)

Distinct gene mutation profiles among multiple and single primary lung adenocarcinoma
por: Wang, Yadong, et al.
Publicado: (2022)

Transdifferentiation of lung adenocarcinoma in mice with Lkb1 deficiency to squamous cell carcinoma
por: Han, Xiangkun, et al.
Publicado: (2014)

Survival Outcomes for Patients with Surgical and Non-Surgical Treatments in Stages I-III Small-Cell Lung Cancer
por: Che, Keying, et al.
Publicado: (2018)

Nanog maintains stemness of Lkb1‐deficient lung adenocarcinoma and prevents gastric differentiation
por: Tong, Xinyuan, et al.
Publicado: (2021)

Expression profiling and microRNA regulation of the LKB1 pathway in young and aged lung adenocarcinoma patients
por: Boldrini, Laura, et al.
Publicado: (2018)

Glucocorticoid mediated inhibition of LKB1 mutant non-small cell lung cancers
por: Huffman, Kenneth E., et al.
Publicado: (2023)

Author Correction: Transdifferentiation of lung adenocarcinoma in mice with Lkb1 deficiency to squamous cell carcinoma
por: Han, Xiangkun, et al.
Publicado: (2022)

The hexosamine biosynthesis pathway is a targetable liability in KRAS/LKB1-mutant lung cancer
por: Kim, Jiyeon, et al.
Publicado: (2020)

Identification and Validation of a Three Pyroptosis-Related lncRNA Signature for Prognosis Prediction in Lung Adenocarcinoma
por: Liu, Jichang, et al.
Publicado: (2022)

Cezanne promoted autophagy through PIK3C3 stabilization and PIK3C2A transcription in lung adenocarcinoma
por: Wang, Yadong, et al.
Publicado: (2023)

RhoBTB Proteins Regulate the Hippo Pathway by Antagonizing Ubiquitination of LKB1
por: Nguyen, Thanh Hung, et al.
Publicado: (2020)

Mild Oxidative Stress Reduces NRF2 SUMOylation to Promote Kras/Lkb1/Keap1 Mutant Lung Adenocarcinoma Cell Migration and Invasion
por: Xu, Jiaqian, et al.
Publicado: (2020)

Decreased LKB1 predicts poor prognosis in Pancreatic Ductal Adenocarcinoma
por: Yang, Jian-Yu, et al.
Publicado: (2015)

Subcellular localization of β-arrestin1 and its prognostic value in lung adenocarcinoma
por: Li, Xiaowei, et al.
Publicado: (2017)

LKB1 suppression promotes cardiomyocyte regeneration via LKB1-AMPK-YAP axis
por: Qu, Shuang, et al.
Publicado: (2022)

Phenformin enhances the therapeutic effect of selumetinib in KRAS-mutant non-small cell lung cancer irrespective of LKB1 status
por: Zhang, Jun, et al.
Publicado: (2017)

The CREB coactivator CRTC2 promotes oncogenesis in LKB1-mutant non–small cell lung cancer
por: Rodón, Laura, et al.
Publicado: (2019)

CPS1 maintains pyrimidine pools and DNA synthesis in KRAS/LKB1-mutant lung cancer cells
por: Kim, Jiyeon, et al.
Publicado: (2017)

Targeting PGM3 as a Novel Therapeutic Strategy in KRAS/LKB1 Co-Mutant Lung Cancer
por: Lee, Hyunmin, et al.
Publicado: (2022)

ULK1 inhibition overcomes compromised antigen presentation and restores antitumor immunity in LKB1 mutant lung cancer
por: Deng, Jiehui, et al.
Publicado: (2021)

Corrigendum: Decreased LKB1 predicts poor prognosis in Pancreatic Ductal Adenocarcinoma
por: Yang, Jian-Yu, et al.
Publicado: (2015)

Role of LKB1 in lung cancer development
por: Makowski, L, et al.
Publicado: (2008)

Identification of ubiquitinated substrate proteins and their gene expression patterns in lung adenocarcinoma
por: Xu, Ran, et al.
Publicado: (2021)

High PKD2 predicts poor prognosis in lung adenocarcinoma via promoting Epithelial–mesenchymal Transition
por: Pang, Zhaofei, et al.
Publicado: (2019)

Prognostic alternative splicing events related splicing factors define the tumor microenvironment and pharmacogenomic landscape in lung adenocarcinoma
por: Liu, Jichang, et al.
Publicado: (2022)

KRAS/LKB1 and KRAS/TP53 co-mutations create divergent immune signatures in lung adenocarcinomas
por: Gu, Meichen, et al.
Publicado: (2021)

CDK4/6 inhibition triggers ICAM1-driven immune response and sensitizes LKB1 mutant lung cancer to immunotherapy
por: Bai, Xue, et al.
Publicado: (2023)

Niche-Dependent Regulation of Lkb1 in the Proliferation of Lung Epithelial Progenitor Cells
por: Ma, Qingwen, et al.
Publicado: (2022)

PTBP3 mediates TGF-β-induced EMT and metastasis of lung adenocarcinoma
por: Dong, Chenglai, et al.
Publicado: (2022)

The level of oncogenic Ras determines the malignant transformation of Lkb1 mutant tissue in vivo
por: Rackley, Briana, et al.
Publicado: (2021)

Linear ubiquitination of LKB1 activates AMPK pathway to inhibit NLRP3 inflammasome response and reduce chondrocyte pyroptosis in osteoarthritis
por: Chen, Yang, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_2mejs3bdv9gf0cue9djlr6kra6