Cargando…

A Novel Reciprocal Crosstalk between RNF168 and PARP1 to Regulate DNA Repair Processes

Emerging evidence has suggested that cellular crosstalk between RNF168 and poly(ADP-ribose) polymerase 1 (PARP1) contributes to the precise control of the DNA damage response (DDR). However, the direct and reciprocal functional link between them remains unclear. In this report, we identified that RN...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kim, Jae Jin, Lee, Seo Yun, Kim, Soyeon, Chung, Jee Min, Kwon, Mira, Yoon, Jung Hyun, Park, Sangwook, Hwang, Yiseul, Park, Dongsun, Lee, Jong-Soo, Kang, Ho Chul
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Korean Society for Molecular and Cellular Biology 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6125419/ https://www.ncbi.nlm.nih.gov/pubmed/30037213 http://dx.doi.org/10.14348/molcells.2018.0078

Ejemplares similares

Stress-induced NEDDylation promotes cytosolic protein aggregation through HDAC6 in a p62-dependent manner
por: Kim, Soyeon, et al.
Publicado: (2021)

Calling RNF168 to action
por: Nowsheen, Somaira, et al.
Publicado: (2018)

RNF126 Quenches RNF168 Function in the DNA Damage Response
por: Zhang, Lianzhong, et al.
Publicado: (2018)

Emerging Roles of RNF168 in Tumor Progression
por: Xie, Tianyuan, et al.
Publicado: (2023)

UBA80 and UBA52 fine-tune RNF168-dependent histone ubiquitination and DNA repair
por: Lee, Seong-Ok, et al.
Publicado: (2023)

Regulation of 53BP1 Protein Stability by RNF8 and RNF168 Is Important for Efficient DNA Double-Strand Break Repair
por: Hu, Yiheng, et al.
Publicado: (2014)

BCL10 regulates RNF8/RNF168-mediated ubiquitination in the DNA damage response
por: Zhao, Hongchang, et al.
Publicado: (2014)

USP39 promotes non-homologous end-joining repair by poly(ADP-ribose)-induced liquid demixing
por: Kim, Jae Jin, et al.
Publicado: (2021)

Clinical and Biological Manifestation of RNF168 Deficiency in Two Polish Siblings
por: Pietrucha, Barbara, et al.
Publicado: (2017)

RNF168 cooperates with RNF8 to mediate FOXM1 ubiquitination and degradation in breast cancer epirubicin treatment
por: Kongsema, M, et al.
Publicado: (2016)

Opposing roles of RNF8/RNF168 and deubiquitinating enzymes in ubiquitination-dependent DNA double-strand break response signaling and DNA-repair pathway choice
por: Nakada, Shinichiro
Publicado: (2016)

DNA damage-induced histone H1 ubiquitylation is mediated by HUWE1 and stimulates the RNF8-RNF168 pathway
por: Mandemaker, I. K., et al.
Publicado: (2017)

The RNF168 paralog RNF169 defines a new class of ubiquitylated histone reader involved in the response to DNA damage
por: Kitevski-LeBlanc, Julianne, et al.
Publicado: (2017)

RNF168 facilitates oestrogen receptor ɑ transcription and drives breast cancer proliferation
por: Liu, Zhenhua, et al.
Publicado: (2018)

Put a RING on it: regulation and inhibition of RNF8 and RNF168 RING finger E3 ligases at DNA damage sites
por: Bartocci, Cristina, et al.
Publicado: (2013)

L3MBTL2 orchestrates ubiquitin signaling by dictating the sequential recruitment of RNF8 and RNF168 after DNA damage
por: Nowsheen, Somaira, et al.
Publicado: (2018)

Effects of pH and Osmotic Changes on the Metabolic Expressions of Bacillus subtilis Strain 168 in Metabolite Pathways including Leucine Metabolism
por: Park, Min-Kyung, et al.
Publicado: (2022)

Ubiquitin-H2AX fusions render 53BP1 recruitment to DNA damage sites independent of RNF8 or RNF168
por: Kocyłowski, Maciej K, et al.
Publicado: (2015)

RNF168 facilitates proliferation and invasion of esophageal carcinoma, possibly via stabilizing STAT1
por: Yu, Na, et al.
Publicado: (2018)

A protocol to visualize cytosolic aggresome-like bodies using confocal microscopy
por: Kim, Soyeon, et al.
Publicado: (2021)

PARP1-MGMT complex underpins pathway crosstalk in O(6)-methylguanine repair
por: Cropper, Jodie D., et al.
Publicado: (2022)

The RNF8 and RNF168 Ubiquitin Ligases Regulate Pro- and Anti-Resection Activities at Broken DNA Ends During Non-Homologous End Joining
por: Chen, Bo-Ruei, et al.
Publicado: (2021)

Structural insights into two distinct binding modules for Lys63-linked polyubiquitin chains in RNF168
por: Takahashi, Tomio S., et al.
Publicado: (2018)

Structural basis of specific H2A K13/K15 ubiquitination by RNF168
por: Horn, Velten, et al.
Publicado: (2019)

MRE11 and UBR5 Co-Operate to Suppress RNF168-Mediated Fusion of Dysfunctional Telomeres
por: Tang, Yongjian, et al.
Publicado: (2021)

Novel Combined Immune Deficiency and Radiation Sensitivity Blended Phenotype in an Adult with Biallelic Variations in ZAP70 and RNF168
por: Chinn, Ivan K., et al.
Publicado: (2017)

The HDAC6-RNF168 axis regulates H2A/H2A.X ubiquitination to enable double-strand break repair
por: Qiu, Lingyu, et al.
Publicado: (2023)

Ectopic expression of RNF168 and 53BP1 increases mutagenic but not physiological non-homologous end joining
por: Zong, Dali, et al.
Publicado: (2015)

RNF168 and USP10 regulate topoisomerase IIα function via opposing effects on its ubiquitylation
por: Guturi, Kiran Kumar Naidu, et al.
Publicado: (2016)

The mTOR-S6K Pathway Links Growth Signaling to DNA Damage Response by Targeting RNF168
por: Xie, Xiaoduo, et al.
Publicado: (2018)

Retroviral insertional mutagenesis implicates E3 ubiquitin ligase RNF168 in the control of cell proliferation and survival
por: Kizilors, Aytug, et al.
Publicado: (2017)

Ectopic RNF168 expression promotes break-induced replication-like DNA synthesis at stalled replication forks
por: Krais, John J, et al.
Publicado: (2020)

Histone H2A variants alpha1-extension helix directs RNF168-mediated ubiquitination
por: Kelliher, Jessica L., et al.
Publicado: (2020)

RNF168-mediated localization of BARD1 recruits the BRCA1-PALB2 complex to DNA damage
por: Krais, John J., et al.
Publicado: (2021)

A novel ubiquitin mark at the N-terminal tail of histone H2As targeted by RNF168 ubiquitin ligase
por: Gatti, Marco, et al.
Publicado: (2012)

The nucleosome acidic patch plays a critical role in RNF168-dependent ubiquitination of histone H2A
por: Mattiroli, Francesca, et al.
Publicado: (2014)

A PALB2-interacting domain in RNF168 couples homologous recombination to DNA break-induced chromatin ubiquitylation
por: Luijsterburg, Martijn S, et al.
Publicado: (2017)

Expression of HYOU1 via Reciprocal Crosstalk between NSCLC Cells and HUVECs Control Cancer Progression and Chemoresistance in Tumor Spheroids
por: Lee, Minji, et al.
Publicado: (2021)

An RNF168 fragment defective for focal accumulation at DNA damage is proficient for inhibition of homologous recombination in BRCA1 deficient cells
por: Muñoz, Meilen C., et al.
Publicado: (2014)

Erratum: The nucleosome acidic patch plays a critical role in RNF168-dependent ubiquitination of histone H2A
por: Mattiroli, Francesca, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_hde9ti28b4q88r3uqeqlomq3jp