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Aberrant methylation and silencing of the SPINT2 gene in high‐grade gliomas

Hepatocyte growth factor activator inhibitor type 2 (HAI‐2), encoded by the SPINT2 gene, is a membrane‐anchored protein that inhibits proteases involved in the activation of hepatocyte growth factor (HGF), a ligand of MET receptor. Epigenetic silencing of the SPINT2 gene has been reported in a human...

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Detalles Bibliográficos
Autores principales:	Fukushima, Tsuyoshi, Kawaguchi, Makiko, Yamamoto, Koji, Yamashita, Fumiki, Izumi, Aya, Kaieda, Takashi, Takezaki, Yuka, Itoh, Hiroshi, Takeshima, Hideo, Kataoka, Hiroaki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2018
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6125435/ https://www.ncbi.nlm.nih.gov/pubmed/29987920 http://dx.doi.org/10.1111/cas.13732

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