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EWS‐FLI1 regulates a transcriptional program in cooperation with Foxq1 in mouse Ewing sarcoma

EWS‐FLI1 constitutes an oncogenic transcription factor that plays key roles in Ewing sarcoma development and maintenance. We have recently succeeded in generating an ex vivo mouse model for Ewing sarcoma by introducing EWS‐FLI1 into embryonic osteochondrogenic progenitors. The model well recapitulat...

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Detalles Bibliográficos
Autores principales: Shimizu, Rikuka, Tanaka, Miwa, Tsutsumi, Shuichi, Aburatani, Hiroyuki, Yamazaki, Yukari, Homme, Mizuki, Kitagawa, Yoshimasa, Nakamura, Takuro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6125457/
https://www.ncbi.nlm.nih.gov/pubmed/29945296
http://dx.doi.org/10.1111/cas.13710

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