E-hooks provide guidance and a soft landing for the microtubule binding domain of dynein

Macromolecular binding is a complex process that involves sensing and approaching the binding partner, adopting the proper orientation, and performing the physical binding. We computationally investigated the role of E-hooks, which are intrinsically disordered regions (IDRs) at the C-terminus of tub...

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Detalles Bibliográficos
Autores principales: Tajielyato, Nayere, Li, Lin, Peng, Yunhui, Alper, Joshua, Alexov, Emil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6125590/
https://www.ncbi.nlm.nih.gov/pubmed/30185874
http://dx.doi.org/10.1038/s41598-018-31480-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6125590/
https://www.ncbi.nlm.nih.gov/pubmed/30185874
http://dx.doi.org/10.1038/s41598-018-31480-9

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