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E-hooks provide guidance and a soft landing for the microtubule binding domain of dynein
Macromolecular binding is a complex process that involves sensing and approaching the binding partner, adopting the proper orientation, and performing the physical binding. We computationally investigated the role of E-hooks, which are intrinsically disordered regions (IDRs) at the C-terminus of tub...
Autores principales: | Tajielyato, Nayere, Li, Lin, Peng, Yunhui, Alper, Joshua, Alexov, Emil |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6125590/ https://www.ncbi.nlm.nih.gov/pubmed/30185874 http://dx.doi.org/10.1038/s41598-018-31480-9 |
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