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Association of the IP3R to STIM1 provides a reduced intraluminal calcium microenvironment, resulting in enhanced store-operated calcium entry

The involvement of inositol trisphosphate receptor (IP3R) in modulating store-operated calcium entry (SOCE) was established many years ago. Nevertheless, the molecular mechanism responsible for this observation has not been elucidated to this date. In the present study we show that IP3R associates t...

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Detalles Bibliográficos
Autores principales: Sampieri, Alicia, Santoyo, Karla, Asanov, Alexander, Vaca, Luis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6125598/
https://www.ncbi.nlm.nih.gov/pubmed/30185837
http://dx.doi.org/10.1038/s41598-018-31621-0