Bidirectional regulation of adenosine-to-inosine (A-to-I) RNA editing by DEAH box helicase 9 (DHX9) in cancer

Adenosine-to-inosine (A-to-I) RNA editing entails the enzymatic deamination of adenosines to inosines by adenosine deaminases acting on RNA (ADARs). Dysregulated A-to-I editing has been implicated in various diseases, including cancers. However, the precise factors governing the A-to-I editing and t...

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Detalles Bibliográficos
Autores principales: Hong, HuiQi, An, Omer, Chan, Tim H M, Ng, Vanessa H E, Kwok, Hui Si, Lin, Jaymie S, Qi, Lihua, Han, Jian, Tay, Daryl J T, Tang, Sze Jing, Yang, Henry, Song, Yangyang, Bellido Molias, Fernando, Tenen, Daniel G, Chen, Leilei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
RNA and RNA-protein complexes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6125626/
https://www.ncbi.nlm.nih.gov/pubmed/29796672
http://dx.doi.org/10.1093/nar/gky396

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